Chlamydia pneumoniae and Rosacea
نویسنده
چکیده
Oral azithromycin has been used successfully to treat rosacea, a chronic skin disease that requires long-term therapy. A study was undertaken to determine if C. pneumoniae could play a causative role in acne rosacea. A series of 10 adults presenting with acne rosacea were selected to receive azithromycin alone for the treatment of acne rosacea. C. pneumoniae was detected in cheek biopsy specimens in 4 of 10 patients by immunoperoxidase stain (using monoclonal antibody to C. pneumoniae) and serum antibody against C. pneumoniae was detected in 8 of 10 patients. Fernandez-Obregon and Patton showed that all patients treated with azithromycin (250 mg three times a week) showed moderate to marked improvement of their rosacea without any undesirable side effect. These preliminary data imply a possible link between C. pneumoniae and acne rosacea as well as suggest a need for further investigation with clinical trials (22)."
منابع مشابه
SIMULTANEOUS DETECTION OF CHLAMYDIA PNEUlvlONIAE AND MYCOPLASMA PNEUMONIAE BY PCR
Both C. pneumoniae and M. pneumoniae are common causes of respiratory tract infection. At present, both are still diagnosed in the laboratory retrospectively by serology. This is despite many publications which indicate that PCR, which is not retrospective, is extremely good at detecting these organisms. We thought that a single PCR test which could detect both organisms simultaneously in a...
متن کاملHigh Sensitivity C–Reactive Protein and Im-munoglobulin G against Chlamydia Pneumo-niae and Chlamydial Heat Shock Protein-60 in Ischemic Heart Disease
Background: Inflammation and infectious agents such as Chlamydia pneumoniae have been associated with cardiovascular disease. Objective: To evaluate the serum high sensitivity C - reactive protein (hs-CRP) and antibodies against Chlamydia pneumoniae and Chlamydial heat shock protein-60 (Cp-HSP60) in patients with ischemic heart disease (IHD). Methods: 62 patients with IHD having either acute my...
متن کاملبررسی فراوانی عفونت کلامیدیا پنومونیه در نسج آدنوئید کودکان آدنوئیدکتومی شده در مجتمع حضرت رسول اکرم(ص) تهران، 85-1384
Background & Aim: Recurrent or chronic adenotonsillar infections mainly affect children. The prevalence of potential respiratory pathogens on the adenoid and tonsillar surfaces of children with moderate symptoms of recurrent tonsillopharyngitis and/or adeno tonsillar hypertrophy differs only slightly from that in children without symptoms of adenotonsillar disease. Chlamydia pneumoniae is a...
متن کاملChlamydia pneumoniae elementary body antigenic reactivity with fluorescent antibody is destroyed by methanol.
Methanol, used for fixing chlamydia organisms to microscopic slides, was shown to eliminate the antigenic reactivity of Chlamydia pneumoniae elementary bodies with fluorescent antibodies. Acetone fixation had no adverse effect. Chlamydia trachomatis and Chlamydia psittaci were not affected by methanol fixation. The effect of methanol on C. pneumoniae is another characteristic that differentiate...
متن کاملChlamydia serology: The value of antibody determinations against recombinant chlamydia specific lipopolysaccha- ride (rLPS) in respiratory infections
Taxonomy The order chlamydiales has one family, chlamydiaceae, and one genus, chlamydia. Currently four species are recognized, Chlamydia trachomatis, Chlamydia pneumoniae, Chlamydia psittaci , and Chlamydia pecorum. To date, 19 different Chlamydia trachomatis serovars (41) and several Chlamydia psittaci serovars are known (6 avian (65), 9 mammalian (29)), but only one Chlamydia pneumoniae (40,...
متن کامل